Grey market peptides have built a parallel pharmaceutical infrastructure under the thinnest regulatory pretense. The data reveals a cultural contradiction that extends far beyond weight loss.
Thanks for the credit on "morphological freedom" and The Transhumanist Reader. Someone pointed out this essay because of that, leading me to read this informative and fascinating piece. I have tried a couple of peptides but had no noticeable results. Something to look into further.
Great essay. We’ve seen a tremendous uptick in folks using our platform (Goodlabs) all across the country for affordable access to blood tests and our AI chat. “Biohacking” is very much NOT just a coastal elite phenomenon anymore. Excited to see what 2026 brings.
Curious your take on sourcing these peptides moving from China -> US, or will regulations make it impossible for the compounding to take off on American soil?
very well written. I like the spin in the middle :) If you self experiment always check the safety via lab testing. Use longevity-tools.com or similar for blood test interpretation. They have tools dedicated to Liver, Insulin resistance, Kidney... all for free
if these people are so smart for using peptides to get skinny... why did they let themselves get fat in the first place? Hasn't claude told them they need to eat less
Why spend the rest of your life hungry and calorie counting when you can take a safe drug like retatrutide? Many obese people could lose weight through dieting but their bodies add fat back very easily. Makes lifelong dieting very difficult
“Eat less” means different things for different bodies. For the morbidly obese “eat less” will mean eating way under 2000 calories for the rest of their life and gaining back weight the instant they go above their baseline. They will never have a chill homeostasis at a health body weight. Most people throughout history did not have to watch their weight. This drug brings that back
etc etc etc meaningfully address a problem with their body in a way that will not contribute usefully to anyone else while still making the system they are trying to short circuit responsible for mitigating negative outcomes
The people that seem to be upset about peptides working are fitness junkies that lack self control/education with food, too, but use an exercise addiction to stay moderately lean
How would one go about prompting gpt or some other llm in order to get the best advice possible on medical matters? I’ve tried asking it directly with my symptoms but it’s always been subpar, not sure what I’m missing in the prompt
(not medical advice) utilizing it to analyze regular bloodwork along with checking clinical notes for a second opinion. use Claude 4.5 Opus with deep research + web search
Right, but the risk and rates of those side effects are pretty well understood *for the name brand medications* given the trials and the large number of users. I’m curious if anyone is looking at the compounded variants specifically, to see if new and unexpected side effects are cropping up. They’re slightly different at a chemical level.
Love how our peptide rave gets honorable mention here
Thanks for the credit on "morphological freedom" and The Transhumanist Reader. Someone pointed out this essay because of that, leading me to read this informative and fascinating piece. I have tried a couple of peptides but had no noticeable results. Something to look into further.
No problem. Had to do a double take when I saw your name pop up!
Great essay. We’ve seen a tremendous uptick in folks using our platform (Goodlabs) all across the country for affordable access to blood tests and our AI chat. “Biohacking” is very much NOT just a coastal elite phenomenon anymore. Excited to see what 2026 brings.
Curious your take on sourcing these peptides moving from China -> US, or will regulations make it impossible for the compounding to take off on American soil?
very well written. I like the spin in the middle :) If you self experiment always check the safety via lab testing. Use longevity-tools.com or similar for blood test interpretation. They have tools dedicated to Liver, Insulin resistance, Kidney... all for free
if these people are so smart for using peptides to get skinny... why did they let themselves get fat in the first place? Hasn't claude told them they need to eat less
Why spend the rest of your life hungry and calorie counting when you can take a safe drug like retatrutide? Many obese people could lose weight through dieting but their bodies add fat back very easily. Makes lifelong dieting very difficult
Pure weakslop.
If you don't have the self control to simply eat less you have NO BUSINESS messing with experimental drugs.
Goku would never say this
Goku wouldn't say anything. He is retarded
cope & seethe
“Eat less” means different things for different bodies. For the morbidly obese “eat less” will mean eating way under 2000 calories for the rest of their life and gaining back weight the instant they go above their baseline. They will never have a chill homeostasis at a health body weight. Most people throughout history did not have to watch their weight. This drug brings that back
The lowest of iq responses.
They didn't. They're not just for fat people trying to lose weight.
etc etc etc meaningfully address a problem with their body in a way that will not contribute usefully to anyone else while still making the system they are trying to short circuit responsible for mitigating negative outcomes
Is it your belief only natural things can make someone healthier?
The people that seem to be upset about peptides working are fitness junkies that lack self control/education with food, too, but use an exercise addiction to stay moderately lean
How would one go about prompting gpt or some other llm in order to get the best advice possible on medical matters? I’ve tried asking it directly with my symptoms but it’s always been subpar, not sure what I’m missing in the prompt
(not medical advice) utilizing it to analyze regular bloodwork along with checking clinical notes for a second opinion. use Claude 4.5 Opus with deep research + web search
without providing as much context as possible from clinical measurements and notes, it may not be accurate nor useful
Are there any studies specifically analyzing dangerous side effects for compounded GLP-1 users? Cancer rates, etc.?
There are reports of ischemic optic neuropathy and retinal detachment from GLP-1 use. These drugs are regulated for a reason!
Right, but the risk and rates of those side effects are pretty well understood *for the name brand medications* given the trials and the large number of users. I’m curious if anyone is looking at the compounded variants specifically, to see if new and unexpected side effects are cropping up. They’re slightly different at a chemical level.